A systematic survey of the Cys(2)His(2) zinc finger DNA-binding landscape

Cys(2)His(2) zinc fingers (C2H2-ZFs) comprise the largest class of metazoan DNA-binding domains. Despite this domain's well-defined DNA-recognition interface, and its successful use in the design of chimeric proteins capable of targeting genomic regions of interest, much remains unknown about i...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Persikov, Anton V., Wetzel, Joshua L., Rowland, Elizabeth F., Oakes, Benjamin L., Xu, Denise J., Singh, Mona, Noyes, Marcus B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Synthetic Biology and Bioengineering
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330361/
https://ncbi.nlm.nih.gov/pubmed/25593323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1395
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