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Understanding Epistatic Interactions between Genes Targeted by Non-coding Regulatory Elements in Complex Diseases

Genome-wide association studies have proven the highly polygenic architecture of complex diseases or traits; therefore, single-locus-based methods are usually unable to detect all involved loci, especially when individual loci exert small effects. Moreover, the majority of associated single-nucleoti...

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Detalhes bibliográficos
Publicado no:Genomics Inform
Main Authors: Sung, Min Kyung, Bang, Hyoeun, Choi, Jung Kyoon
Formato: Artigo
Idioma:Inglês
Publicado em: Korea Genome Organization 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330252/
https://ncbi.nlm.nih.gov/pubmed/25705156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5808/GI.2014.12.4.181
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