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Chronic high-dose creatine has opposing effects on depression-related gene expression and behavior in intact and sex hormone-treated gonadectomized male and female rats

Creatine is an antioxidant, neuromodulator and key regulator of energy metabolism shown to improve depressive symptoms in humans and animals, especially in females. To better understand the pharmacological effects of creatine, we examined its influence on depression-related hippocampal gene expressi...

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Detalhes bibliográficos
Publicado no:Pharmacol Biochem Behav
Main Authors: Allen, Patricia J., DeBold, Joseph F., Rios, Maribel, Kanarek, Robin B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330125/
https://ncbi.nlm.nih.gov/pubmed/25560941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2014.12.014
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