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The role of dasatinib in the management of chronic myeloid leukemia

Dasatinib is a second-generation tyrosine kinase inhibitor (TKI) for chronic, blastic, or accelerated phase chronic myeloid leukemia (CML) patients who are resistant or intolerant to previous treatment. It potently inhibits BCR/ABL and SRC-family kinases (SRC, LCK, HCK, YES, FYN, FGR, BLK, LYN, FRK)...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Chen, Runzhe, Chen, Baoan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330036/
https://ncbi.nlm.nih.gov/pubmed/25709401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S80207
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