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Epigenetics and autoimmune diseases: the X chromosome-nucleolus nexus

Autoimmune diseases occur more often in females, suggesting a key role for the X chromosome. X chromosome inactivation, a major epigenetic feature in female cells that provides dosage compensation of X-linked genes to avoid overexpression, presents special vulnerabilities that can contribute to the...

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Bibliografische gegevens
Gepubliceerd in:Front Genet
Hoofdauteurs: Brooks, Wesley H., Renaudineau, Yves
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329817/
https://ncbi.nlm.nih.gov/pubmed/25763008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00022
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