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Epigenetics and autoimmune diseases: the X chromosome-nucleolus nexus
Autoimmune diseases occur more often in females, suggesting a key role for the X chromosome. X chromosome inactivation, a major epigenetic feature in female cells that provides dosage compensation of X-linked genes to avoid overexpression, presents special vulnerabilities that can contribute to the...
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| Pubblicato in: | Front Genet |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329817/ https://ncbi.nlm.nih.gov/pubmed/25763008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00022 |
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