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PTEN: Multiple Functions in Human Malignant Tumors
PTEN is the most important negative regulator of the PI3K signaling pathway. In addition to its canonical, PI3K inhibition-dependent functions, PTEN can also function as a tumor suppressor in a PI3K-independent manner. Indeed, the PTEN network regulates a broad spectrum of biological functions, modu...
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Publicado no: | Front Oncol |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329810/ https://ncbi.nlm.nih.gov/pubmed/25763354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00024 |
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