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Characterizing alpha helical properties of Ebola viral proteins as potential targets for inhibition of alpha-helix mediated protein-protein interactions

Ebola, considered till recently as a rare and endemic disease, has dramatically transformed into a potentially global humanitarian crisis. The genome of Ebola, a member of the Filoviridae family, encodes seven proteins. Based on the recently implemented software (PAGAL) for analyzing the hydrophobic...

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Veröffentlicht in:F1000Res
Hauptverfasser: Chakraborty, Sandeep, Rao, Basuthkar J., Asgeirsson, Bjarni, Dandekar, Abhaya
Format: Artigo
Sprache:Inglês
Veröffentlicht: F1000Research 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329671/
https://ncbi.nlm.nih.gov/pubmed/25717367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.5573.3
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