Single arm NCRI phase II study of CHOP in combination with Ofatumumab in induction and maintenance for patients with newly diagnosed Richter’s syndrome

BACKGROUND: Transformation of B-cell chronic lymphocytic leukaemia (B-CLL) to diffuse large B cell lymphoma (DLBCL) (Richter’s syndrome (RS)) is a rare (2-15% of patients) but catastrophic complication of B-CLL. Dose-intense chemotherapy regimens investigated in small single institution trials, but...

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Опубликовано в: :BMC Cancer
Главные авторы: Eyre, Toby A, Clifford, Ruth, Roberts, Corran, Boyle, Lucy, Francis, Anne, Schuh, Anna, Dutton, Susan J
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
Предметы:
Study Protocol
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329650/
https://ncbi.nlm.nih.gov/pubmed/25775024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1048-9
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