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Genetic variation of oxidative phosphorylation genes in stroke and Alzheimer’s disease

Previous research implicates alterations in oxidative phosphorylation (OXPHOS) in the development of Alzheimer’s disease (AD). We sought to test whether genetic variants within OXPHOS genes increase the risk of AD. We first used gene-set enrichment analysis to identify associations, and then applied...

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Détails bibliographiques
Publié dans:Neurobiol Aging
Auteurs principaux: Biffi, Alessandro, Sabuncu, Mert R., Desikan, Rahul S., Schmansky, Nick, Salat, David H., Rosand, Jonathan, Anderson, Christopher D.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329419/
https://ncbi.nlm.nih.gov/pubmed/24650791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.01.141
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