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Decreased Cezanne expression is associated with the progression and poor prognosis in hepatocellular carcinoma

BACKGROUND: Deubiquitinases, such as CYLD, A20 and Cezanne, have emerged as negative regulators that balance the strength and duration of NF-κB signaling through feedback mechanisms. However, how these serial feedback loops are simultaneously disrupted in cancer remains unclear. The purpose of this...

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Veröffentlicht in:J Transl Med
Hauptverfasser: Wang, Jia-hong, Wei, Wei, Guo, Zhi-xing, Shi, Ming, Guo, Rong-ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329219/
https://ncbi.nlm.nih.gov/pubmed/25638165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0396-1
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