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The role of polycomb group protein Bmi-1 and Notch4 in breast cancer stem cell inhibition by benzyl isothiocyanate

We showed previously that garden cress constituent benzyl isothiocyanate (BITC) inhibits self-renewal of breast cancer stem cells (bCSC) in vitro and in vivo. The present study offers novel insights into the mechanism by which BITC inhibits bCSC. Flow cytometry and mammosphere assay was performed to...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Kim, Su-Hyeong, Singh, Shivendra V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329083/
https://ncbi.nlm.nih.gov/pubmed/25663545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-015-3279-5
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