Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells

RNA splicing is a fundamental process for protein synthesis. Recent studies have reported that drugs that inhibit splicing have cytotoxic effects on various tumor cell lines. In this report, we demonstrate that depletion of SNW1, a component of the spliceosome, induces apoptosis in breast cancer cel...

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發表在:Cancer Med
Main Authors: Sato, Naoki, Maeda, Masao, Sugiyama, Mai, Ito, Satoko, Hyodo, Toshinori, Masuda, Akio, Tsunoda, Nobuyuki, Kokuryo, Toshio, Hamaguchi, Michinari, Nagino, Masato, Senga, Takeshi
格式: Artigo
語言:Inglês
出版: BlackWell Publishing Ltd 2015
主題:
Cancer Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329010/
https://ncbi.nlm.nih.gov/pubmed/25450007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.366
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