Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells

RNA splicing is a fundamental process for protein synthesis. Recent studies have reported that drugs that inhibit splicing have cytotoxic effects on various tumor cell lines. In this report, we demonstrate that depletion of SNW1, a component of the spliceosome, induces apoptosis in breast cancer cel...

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Bibliografiska uppgifter
I publikationen:Cancer Med
Huvudupphovsmän: Sato, Naoki, Maeda, Masao, Sugiyama, Mai, Ito, Satoko, Hyodo, Toshinori, Masuda, Akio, Tsunoda, Nobuyuki, Kokuryo, Toshio, Hamaguchi, Michinari, Nagino, Masato, Senga, Takeshi
Materialtyp: Artigo
Språk:Inglês
Publicerad: BlackWell Publishing Ltd 2015
Ämnen:
Cancer Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329010/
https://ncbi.nlm.nih.gov/pubmed/25450007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.366
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