Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells

RNA splicing is a fundamental process for protein synthesis. Recent studies have reported that drugs that inhibit splicing have cytotoxic effects on various tumor cell lines. In this report, we demonstrate that depletion of SNW1, a component of the spliceosome, induces apoptosis in breast cancer cel...

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Библиографические подробности
Опубликовано в: :Cancer Med
Главные авторы: Sato, Naoki, Maeda, Masao, Sugiyama, Mai, Ito, Satoko, Hyodo, Toshinori, Masuda, Akio, Tsunoda, Nobuyuki, Kokuryo, Toshio, Hamaguchi, Michinari, Nagino, Masato, Senga, Takeshi
Формат: Artigo
Язык:Inglês
Опубликовано: BlackWell Publishing Ltd 2015
Предметы:
Cancer Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329010/
https://ncbi.nlm.nih.gov/pubmed/25450007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.366
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