Reproducibility of Her2/neu scoring in gastric cancer and assessment of the 10% cut-off rule

The application of Trastuzumab on gastric cancer patients is based on Her2/neu immunostaining. The testing method relies on visual estimation of both membranous staining intensity, and positive tumor ratio with respect to a 10% cutoff. We evaluated the effect of inter- and intraobserver variations o...

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Foilsithe in:Cancer Med
Main Authors: Behrens, Hans-Michael, Warneke, Viktoria S, Böger, Christine, Garbrecht, Nele, Jüttner, Eva, Klapper, Wolfram, Mathiak, Micaela, Oschlies, Ilske, Rudolph, Ursula, Stuhlmann-Laeisz, Christiane, Trick, David, Röcken, Christoph, Hufnagl, Peter
Formáid: Artigo
Teanga:Inglês
Foilsithe: BlackWell Publishing Ltd 2015
Ábhair:
Cancer Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329007/
https://ncbi.nlm.nih.gov/pubmed/25515030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.365
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