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Antiproliferative and metabolic effects of metformin in a preoperative window clinical trial for endometrial cancer

We conducted a preoperative window study of metformin in endometrial cancer (EC) patients and evaluated its antiproliferative, molecular and metabolic effects. Twenty obese women with endometrioid EC were treated with metformin (850 mg) daily for up to 4 weeks prior to surgical staging. Expression o...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Schuler, Kevin M, Rambally, Brooke S, DiFurio, Megan J, Sampey, Brante P, Gehrig, Paola A, Makowski, Liza, Bae-Jump, Victoria L
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329001/
https://ncbi.nlm.nih.gov/pubmed/25417601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.353
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