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DNA polyintercalating drugs: DNA binding of diacridine derivatives.

As a first step in the synthesis and the study of DNA polyintercalating drugs, dimers of acridines have been prepared. Their DNA binding properties have been studied. It has been determined that when the chain separating the two aromatic rings is longer than a criticål distance, bisintercalation is...

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Autors principals: Le Pecq, J B, Le Bret, M, Barbet, J, Roques, B
Format: Artigo
Idioma:Inglês
Publicat: 1975
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC432889/
https://ncbi.nlm.nih.gov/pubmed/127172
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