ONCOSTATIN M BINDS TO EXTRACELLULAR MATRIX IN A BIOACTIVE CONFORMATION: IMPLICATIONS FOR INFLAMMATION AND METASTASIS

Oncostatin M (OSM) is an interleukin-6-like inflammatory cytokine reported to play a role in a number of pathological processes including cancer. Full-length OSM is expressed as a 26 kDa protein that can be proteolytically processed into 24 kDa and 22 kDa forms via removal of C-terminal peptides. In...

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Detalles Bibliográficos
Publicado en:Cytokine
Main Authors: Ryan, Randall, Martin, Bryan, Mellor, Liliana, Jacob, Reed B., Tawara, Ken, McDougal, Owen M., Oxford, Julia Thom, Jorcyk, Cheryl L.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4328881/
https://ncbi.nlm.nih.gov/pubmed/25622278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2014.11.007
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