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Molecular physiopathogenetic mechanisms and development of new potential therapeutic strategies in persistent pulmonary hypertension of the newborn

Persistent pulmonary hypertension of the newborn (PPHN) is a cyanogenic plurifactorial disorder characterized by failed postnatal drop of pulmonary vascular resistance and maintenance of right-to-left shunt across ductus arteriosus and foramen ovale typical of intrauterine life. The pathogenesis of...

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Publicat a:Ital J Pediatr
Autors principals: Distefano, Giuseppe, Sciacca, Pietro
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4328557/
https://ncbi.nlm.nih.gov/pubmed/25887340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13052-015-0111-0
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