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Antigen-induced conformational changes in antibodies and their Fab fragments studied by circular polarization of fluorescence.

Conformational changes induced in antibody molecules and in their Fab fragments by binding of antigen were investigated by the circular polarization of the fluorescence emitted by the tryptophan residues. This property of the fluorescence is related to the asymmetry, and thus to the conformation and...

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Detalhes bibliográficos
Main Authors: Schlessinger, J, Steinberg, I Z, Givol, D, Hochman, J, Pecht, I
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC432854/
https://ncbi.nlm.nih.gov/pubmed/1058492
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