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Conditional-lethal mutations that suppress genetic defects in morphogenesis by altering structural proteins.

An analysis of revertants of missense mutants in phage P22 has shown: (i) New temperature-sensitive (TS) and cold-sensitive (CS) phenotypes are often acquired concomitant with reversion. (ii) In many cases, these new phenotypes are due to second-site mutations (suppressors) that correct the original...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Jarvik, J, Botstein, D
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1975
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432846/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1101263/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.7.2738
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