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Association of high-molecular-weight proteins with microtubules and their role in microtubule assembly in vitro.

High-molecular-weight components (HMW) specifically associated with microtubule protein purified from porcine brain tissue were separated from tubulin by DEAE-Sephadex ion exchange chromatography. Analysis by viscometry, sedimentation, and electron microscopy of the unfractionated microtubule protei...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Murphy, D B, Borisy, G G
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1975
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432837/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1058484/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.7.2696
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