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Minimal requirements for template recognition by bacteriophage Qβ replicase: Approach to general RNA-dependent RNA synthesis

Any oligo- or polynucleotide able to offer a C-C-C-sequence at the 3′-terminus and a second C-C-C-sequence in a defined steric position to Qβ replicase is an efficient template. Corresponding chemical modifications convert non-template RNAs to template RNAs. IMAGES:

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Küppers, Bernd, Sumper, Manfred
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1975
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432825/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1058479/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.7.2640
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