Sex Differences in Biomarkers Associated With Insulin Resistance in Obese Adolescents: Metabolomic Profiling and Principal Components Analysis

OBJECTIVE: Obesity and insulin resistance (IR) predispose to type 2 diabetes mellitus. Yet only half of obese adolescents have IR and far fewer progress to type 2 diabetes mellitus. We hypothesized that amino acid and fatty acid metabolites may serve as biomarkers or determinants of IR in obese teen...

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Publié dans:J Clin Endocrinol Metab
Auteurs principaux: Newbern, Dorothee, Gumus Balikcioglu, Pinar, Balikcioglu, Metin, Bain, James, Muehlbauer, Michael, Stevens, Robert, Ilkayeva, Olga, Dolinsky, Diana, Armstrong, Sarah, Irizarry, Krystal, Freemark, Michael
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2014
Sujets:
Endocrine Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4328030/
https://ncbi.nlm.nih.gov/pubmed/25202817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-2080
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