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Optimized methods for epilepsy therapy development using an etiologically realistic model of focal epilepsy in the rat

Conventionally developed antiseizure drugs fail to control epileptic seizures in about 30% of patients, and no treatment prevents epilepsy. New etiologically realistic, syndrome-specific epilepsy models are expected to identify better treatments by capturing currently unknown ictogenic and epileptog...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Eastman, Clifford L., Fender, Jason S., Temkin, Nancy R., D’Ambrosio, Raimondo
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327986/
https://ncbi.nlm.nih.gov/pubmed/25523813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.12.010
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