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External blockade of the major cardiac delayed-rectifier K+ channel (Kv1.5) by polyunsaturated fatty acids.

The present work shows that arachidonic acid and some other long chain polyunsaturated fatty acids such as docosahexaenoic acid, which is abundant in fish oil, produce a direct open channel block of the major voltage-dependent K+ channel (Kv1.5) cloned in cardiac cells. The inhibitory action of thes...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Honoré, E, Barhanin, J, Attali, B, Lesage, F, Lazdunski, M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1994
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43279/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127910/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.5.1937
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