Potential Contributions of the Tobacco Nicotine-Derived Nitrosamine Ketone (NNK) in the Pathogenesis of Steatohepatitis in a Chronic Plus Binge Rat Model of Alcoholic Liver Disease

Aims: Alcoholic liver disease (ALD) is linked to binge drinking and cigarette smoking. Heavy chronic ± binge alcohol, or low-level exposures to dietary nitrosamines cause steatohepatitis with insulin resistance and oxidative stress in animal models. This study examines hepatotoxic effects of sub-mut...

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Dades bibliogràfiques
Publicat a:Alcohol Alcohol
Autors principals: Zabala, Valerie, Tong, Ming, Yu, Rosa, Ramirez, Teresa, Yalcin, Emine B., Balbo, Silvia, Silbermann, Elizabeth, Deochand, Chetram, Nunez, Kavin, Hecht, Stephen, de la Monte, Suzanne M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Metabolic and Genetic
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327341/
https://ncbi.nlm.nih.gov/pubmed/25618784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/alcalc/agu083
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