Evidence from studies in rodents and in isolated adipocytes that agonists of the chemerin receptor CMKLR1 may be beneficial in the treatment of type 2 diabetes

The literature is unclear on whether the adipokine chemerin has pro- or anti-inflammatory properties or plays any role in the aetiology of type 2 diabetes or obesity. To address these questions, and in particular the potential of agonists or antagonists of the chemerin receptor CMKLR1 in the treatme...

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Veröffentlicht in:PeerJ
Hauptverfasser: Wargent, Edward T., Zaibi, Mohamed S., O’Dowd, Jacqueline F., Cawthorne, Michael A., Wang, Steven J., Arch, Jonathan R.S., Stocker, Claire J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: PeerJ Inc. 2015
Schlagworte:
Diabetes and Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327305/
https://ncbi.nlm.nih.gov/pubmed/25699203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.753
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