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An Active Immune Defense with a Minimal CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) RNA and without the Cas6 Protein

The prokaryotic immune system CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR-associated) is a defense system that protects prokaryotes against foreign DNA. The short CRISPR RNAs (crRNAs) are central components of this immune system. In CRISPR-Cas systems type I and III,...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Maier, Lisa-Katharina, Stachler, Aris-Edda, Saunders, Sita J., Backofen, Rolf, Marchfelder, Anita
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326828/
https://ncbi.nlm.nih.gov/pubmed/25512373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.617506
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