Hepatocyte Growth Factor-induced Asef-IQGAP1 Complex Controls Cytoskeletal Remodeling and Endothelial Barrier

Hepatocyte growth factor (HGF) attenuates agonist-induced endothelial cell (EC) permeability and increases pulmonary endothelial barrier function via Rac-dependent enhancement of the peripheral actin cytoskeleton. However, the precise mechanisms of HGF effects on the peripheral cytoskeleton are not...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Tian, Yufeng, Gawlak, Grzegorz, Shah, Alok S., Higginbotham, Katherine, Tian, Xinyong, Kawasaki, Yoshihiro, Akiyama, Tetsu, Sacks, David B., Birukova, Anna A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326819/
https://ncbi.nlm.nih.gov/pubmed/25492863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.620377
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