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Resveratrol ameliorates experimental periodontitis in diabetic mice through negative regulation of TLR4 signaling

AIM: To investigate the therapeutic effects of resveratrol (RSV) on periodontitis in diabetic mice and to explore the underlying mechanisms in vitro. METHODS: Experimental periodontitis was induced in db/db mice by ligature application of porphyromonas gingivalis. The mice were treated with RSV (20...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Zhen, Lei, Fan, De-sheng, Zhang, Yan, Cao, Xin-ming, Wang, Li-ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326790/
https://ncbi.nlm.nih.gov/pubmed/25530164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.131
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