Tanshinone IIA therapeutically reduces LPS-induced acute lung injury by inhibiting inflammation and apoptosis in mice

AIM: To study the effects of tanshinone IIA (TIIA) on lipopolysaccharide (LPS)-induced acute lung injury in mice and the underlying mechanisms. METHODS: Mice were injected with LPS (10 mg/kg, ip), then treated with TIIA (10 mg/kg, ip). Seven hours after LPS injection, the lungs were collected for hi...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Xu, Min, Cao, Fa-le, Zhang, Yu-fei, Shan, Liang, Jiang, Xiao-ling, An, Xiao-jing, Xu, Wei, Liu, Xiu-zhi, Wang, Xiao-yan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326786/
https://ncbi.nlm.nih.gov/pubmed/25544360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.112
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