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A population pharmacokinetic study of tacrolimus in healthy Chinese volunteers and liver transplant patients

AIM: To develop a population pharmacokinetic (PopPK) model of tacrolimus in healthy Chinese volunteers and liver transplant recipients for investigating the difference between the populations, and for potential individualized medication. METHODS: A set of 1100 sparse trough concentration data points...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Lu, Yan-xia, Su, Qing-hong, Wu, Ke-hua, Ren, Yu-peng, Li, Liang, Zhou, Tian-yan, Lu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326784/
https://ncbi.nlm.nih.gov/pubmed/25500866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.110
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