P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation

The small GTPase Rac is required for neutrophil recruitment during inflammation, but its guanine-nucleotide exchange factor (GEF) activators seem dispensable for this process, which led us to investigate the possibility of cooperation between Rac-GEF families. Thioglycollate-induced neutrophil recru...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Pan, Dingxin, Amison, Richard T., Riffo-Vasquez, Yanira, Spina, Domenico, Cleary, Simon J., Wakelam, Michael J., Page, Clive P., Pitchford, Simon C., Welch, Heidi C. E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326774/
https://ncbi.nlm.nih.gov/pubmed/25538043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-591040
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