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Simultaneous bile duct and portal vein ligation induces faster atrophy/hypertrophy complex than portal vein ligation: role of bile acids

Portal vein ligation (PVL) induces atrophy/hypertrophy complex (AHC). We hypothesised that simultaneous bile duct and portal vein ligation (BPL) might induce proper bile acid (BA) retention to enhance AHC by activating BA-mediated FXR signalling in the intact liver and promoting apoptosis in the lig...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ren, Weizheng, Chen, Geng, Wang, Xiaofeng, Zhang, Aiqun, Li, Chonghui, Lv, Wenping, Pan, Ke, Dong, Jia-hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326731/
https://ncbi.nlm.nih.gov/pubmed/25678050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08455
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