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Comprehensive massive parallel DNA sequencing strategy for the genetic diagnosis of the neuro-cardio-facio-cutaneous syndromes

Variants in 11 genes of the RAS/MAPK signaling pathway have been causally linked to the neuro-cardio-facio-cutaneous syndromes group (NCFCS). Recently, A2ML1 and RIT1 were also associated with these syndromes. Because of the genetic and clinical heterogeneity of NCFCS, it is challenging to define st...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Eur J Hum Genet
Päätekijät: Justino, Ana, Dias, Patrícia, João Pina, Maria, Sousa, Sónia, Cirnes, Luís, Berta Sousa, Ana, Carlos Machado, José, Costa, José Luis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326724/
https://ncbi.nlm.nih.gov/pubmed/24896146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.97
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