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Sandwich corrected standard errors in family-based genome-wide association studies

Given the availability of genotype and phenotype data collected in family members, the question arises which estimator ensures the most optimal use of such data in genome-wide scans. Using simulations, we compared the Unweighted Least Squares (ULS) and Maximum Likelihood (ML) procedures. The former...

詳細記述

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書誌詳細
出版年:Eur J Hum Genet
主要な著者: Minică, Camelia C, Dolan, Conor V, Kampert, Maarten M D, Boomsma, Dorret I, Vink, Jacqueline M
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326721/
https://ncbi.nlm.nih.gov/pubmed/24916646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.94
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