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Syngap1 haploinsufficiency damages a postnatal critical period of pyramidal cell structural maturation linked to cortical circuit assembly
BACKGROUND: Genetic haploinsufficiency of Syngap1 commonly occurs in developmental brain disorders, such as intellectual disability (ID), epilepsy, schizophrenia (SCZ), and autism spectrum (ASD) disorder. Thus, studying mouse models of Syngap1 haploinsufficiency may uncover pathological developmenta...
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| Publicado no: | Biol Psychiatry |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326604/ https://ncbi.nlm.nih.gov/pubmed/25444158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.08.001 |
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