Denatonium inhibits growth and induces apoptosis of airway epithelial cells through mitochondrial signaling pathways

BACKGROUND: Denatonium, a widely used bitter agonist, activates bitter taste receptors on many cell types and plays important roles in chemical release, ciliary beating and smooth muscle relaxation through intracellular Ca(2+)-dependent pathways. However, the effects of denatonium on the proliferati...

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Gepubliceerd in:Respir Res
Hoofdauteurs: Wen, Xiaoxing, Zhou, Jian, Zhang, Dan, Li, Jing, Wang, Qin, Feng, Nana, Zhu, Haixing, Song, Yuanlin, Li, Huayin, Bai, Chunxue
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326484/
https://ncbi.nlm.nih.gov/pubmed/25652218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0183-9
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