TNF-α Mediates PKCδ/JNK1/2/c-Jun-Dependent Monocyte Adhesion via ICAM-1 Induction in Human Retinal Pigment Epithelial Cells

Retinal inflammatory diseases induced by cytokines, such as tumor necrosis factor-α (TNF-α) are associated with an up-regulation of intercellular adhesion molecule-1 (ICAM-1) in the retinal pigment epithelial cells (RPECs). Retinal pigment epithelium (RPE) is a monolayer of epithelial cells that for...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Lee, I-Ta, Liu, Shiau-Wen, Chi, Pei-Ling, Lin, Chih-Chung, Hsiao, Li-Der, Yang, Chuen-Mao
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326428/
https://ncbi.nlm.nih.gov/pubmed/25675437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117911
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