Transfer of the human gene for hypoxanthine-guanine phosphoribosyltransferase via isolated human metaphase chromosomes into mouse L-cells.

We have transferred the human gene for hypoxanthine-guanine phosphoribosyltransferase (HPRT, EC 2.4.2.8; IMP:pyrophosphate phosphoribosyltransferease) via isolated metaphase chromosomes from human HeLa S3 cells into murine A9 cells which lack functional murine HPRT activity, using the technique of M...

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Detalhes bibliográficos
Main Authors: Willecke, K, Ruddle, F H
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC432632/
https://ncbi.nlm.nih.gov/pubmed/1057170
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