Expansion of CD27(high) plasmablasts in transverse myelitis patients that utilize VH4 and JH6 genes and undergo extensive somatic hypermutation

Patients with the autoimmune disease multiple sclerosis (MS) typically present with the clinically isolated syndromes (CIS) transverse myelitis (TM) or optic neuritis (ON). B-cell disturbances have been well documented in patients with MS and CIS patients with ON, but not in CIS patients with TM, de...

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Detalhes bibliográficos
Publicado no:Genes Immun
Main Authors: Ligocki, AJ, Rounds, WH, Cameron, EM, Harp, CT, Frohman, EM, Courtney, AM, Vernino, S, Cowell, LG, Greenberg, B, Monson, NL
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326094/
https://ncbi.nlm.nih.gov/pubmed/23594958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2013.18
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