Preferential Targeting of Disseminated Liver Tumors Using a Recombinant Adeno-Associated Viral Vector

A novel selectively targeting gene delivery approach has been developed for advanced hepatocellular carcinoma (HCC), a leading cause of cancer mortality whose prognosis remains poor. We combine the strong liver tropism of serotype-8 capsid-pseudotyped adeno-associated viral vectors (AAV8) with a liv...

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Bibliografske podrobnosti
izdano v:Hum Gene Ther
Main Authors: Della Peruta, Marco, Badar, Adam, Rosales, Cecilia, Chokshi, Shilpa, Kia, Azadeh, Nathwani, Devhrut, Galante, Eva, Yan, Ran, Arstad, Erik, Davidoff, Andrew M., Williams, Roger, Lythgoe, Mark F., Nathwani, Amit C.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2015
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326028/
https://ncbi.nlm.nih.gov/pubmed/25569358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2014.052
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