Preferential Targeting of Disseminated Liver Tumors Using a Recombinant Adeno-Associated Viral Vector

A novel selectively targeting gene delivery approach has been developed for advanced hepatocellular carcinoma (HCC), a leading cause of cancer mortality whose prognosis remains poor. We combine the strong liver tropism of serotype-8 capsid-pseudotyped adeno-associated viral vectors (AAV8) with a liv...

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Bibliografski detalji
Izdano u:Hum Gene Ther
Glavni autori: Della Peruta, Marco, Badar, Adam, Rosales, Cecilia, Chokshi, Shilpa, Kia, Azadeh, Nathwani, Devhrut, Galante, Eva, Yan, Ran, Arstad, Erik, Davidoff, Andrew M., Williams, Roger, Lythgoe, Mark F., Nathwani, Amit C.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2015
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326028/
https://ncbi.nlm.nih.gov/pubmed/25569358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2014.052
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