ATP-Induced IL-1β Specific Secretion: True Under Stringent Conditions

Interleukin-1β is a potent proinflammatory cytokine, of which processing and secretion are tightly regulated. After exposure to various stimuli, mononuclear phagocytes synthesize the inactive precursor (pro-IL-1β), which is then cleaved intracellularly by caspase-1 and secreted. A widely used method...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Stoffels, Monique, Zaal, Ruben, Kok, Nina, van der Meer, Jos W. M., Dinarello, Charles A., Simon, Anna
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325933/
https://ncbi.nlm.nih.gov/pubmed/25729382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00054
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