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Fluoroquinolone Resistance Does Not Impose a Cost on the Fitness of Clostridium difficile In Vitro
Point mutations conferring resistance to fluoroquinolones were introduced in the gyr genes of the reference strain Clostridium difficile 630. Only mutants with the substitution Thr-82→Ile in GyrA, which characterizes the hypervirulent epidemic clone III/027/NAP1, were resistant to all fluoroquinolon...
Zapisane w:
| Wydane w: | Antimicrob Agents Chemother |
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| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4325769/ https://ncbi.nlm.nih.gov/pubmed/25534738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04503-14 |
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