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Fluoroquinolone Resistance Does Not Impose a Cost on the Fitness of Clostridium difficile In Vitro
Point mutations conferring resistance to fluoroquinolones were introduced in the gyr genes of the reference strain Clostridium difficile 630. Only mutants with the substitution Thr-82→Ile in GyrA, which characterizes the hypervirulent epidemic clone III/027/NAP1, were resistant to all fluoroquinolon...
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| 發表在: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4325769/ https://ncbi.nlm.nih.gov/pubmed/25534738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04503-14 |
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