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Hepatitis B Virus Regulates Apoptosis and Tumorigenesis through the MicroRNA-15a-Smad7-Transforming Growth Factor Beta Pathway

Hepatitis B virus (HBV) infection causes chronic hepatitis in hundreds of millions of people worldwide, which can eventually lead to hepatocellular carcinoma (HCC). Previously, we found that HBV mRNAs can absorb microRNA-15a (miR-15a) to affect apoptosis through the Bcl-2 pathway. We asked whether H...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Liu, Ningning, Jiao, Tong, Huang, Yan, Liu, Wenjun, Li, Zhiwei, Ye, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325757/
https://ncbi.nlm.nih.gov/pubmed/25540364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02784-14
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