Measles Virus Mutants Possessing the Fusion Protein with Enhanced Fusion Activity Spread Effectively in Neuronal Cells, but Not in Other Cells, without Causing Strong Cytopathology

Subacute sclerosing panencephalitis (SSPE) is caused by persistent measles virus (MV) infection in the central nervous system (CNS). Since human neurons, its main target cells, do not express known MV receptors (signaling lymphocyte activation molecule [SLAM] and nectin 4), it remains to be understo...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Watanabe, Shumpei, Ohno, Shinji, Shirogane, Yuta, Suzuki, Satoshi O., Koga, Ritsuko, Yanagi, Yusuke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325728/
https://ncbi.nlm.nih.gov/pubmed/25520515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03346-14
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