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Virion-Independent Transfer of Replication-Competent Hepatitis C Virus RNA between Permissive Cells

In this study, we show that replication-competent subgenomic hepatitis C virus (HCV) RNA can be transferred to permissive Huh7 cells, leading to the establishment of viral RNA replication. Further, we show that these events are mediated by exosomes rather than infectious virus particles. If similar...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Longatti, Andrea, Boyd, Bryan, Chisari, Francis V.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325714/
https://ncbi.nlm.nih.gov/pubmed/25505060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02721-14
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