Advantages and applications of CAR-expressing natural killer cells

In contrast to donor T cells, natural killer (NK) cells are known to mediate anti-cancer effects without the risk of inducing graft-versus-host disease (GvHD). In order to improve cytotoxicity against resistant cancer cells, auspicious efforts have been made with chimeric antigen receptor (CAR) expr...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Glienke, Wolfgang, Esser, Ruth, Priesner, Christoph, Suerth, Julia D., Schambach, Axel, Wels, Winfried S., Grez, Manuel, Kloess, Stephan, Arseniev, Lubomir, Koehl, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325659/
https://ncbi.nlm.nih.gov/pubmed/25729364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00021
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